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Tumor suppressor genes get a notable boost as well
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24 For this reason, SSRIs should be used in caution in those patients on anticoagulants or at higher risk of bleeding
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However, this is considered an underestimation as it will be unlikely to be detected in smaller clinical trials, and a more recent study in 2010 found that NSAIDs including ibuprofen (odds ratio of 2.24, 95% confidence interval (CI) = 1.992.52) increased the risk of hospitalization due to acute hepatitis (odds ratio 2.13, 95% CI = 22.18) 35
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